SR9009 pill 100 papa / ʻōmole

Inoa mea kūʻai:SR9009

Spacification: 10 mg/pill 100 pills/boule

Kumukuai:$80/'ōmole

MOQ:1'ōmole

Lab: LianFu Bio

Hōʻike huahana

SR9009, he REV-ERBagonist, hoʻonui i ka repression constitutive o nā genes i hoʻoponoponoʻia e REV-ERBα / ERBβ (IC50: 670/800 nM).Ma o ka ho'ā ʻana o REV-ERB, hiki i ka SR9009 ke hoʻemi i ka hana locomotor circadian i ka wā pōʻeleʻele a hoʻololi i ke ʻano o ka hōʻike ʻana o nā gene clock clock i ka hypothalami o nā ʻiole.Ua hoʻololi pū ʻia ke ʻano circadian o ka hōʻike ʻana o nā ʻano genes metabolic i loko o ke akepaʻa, ka ʻiʻo iwi, a me ka ʻiʻo adipose i nā ʻiole i hōʻike ʻia i ka SR9009, ka hopena o ka hoʻonui ʻana i ka ikehu.

Hiki iā SR9009 (100 mg/kg, ip, bid, no 30 lā).hoemi i ka momonaa me ka hoailonahoʻomaikaʻi i ka dyslipidemiaahyperglycemia.