ʻO Adipotide 2mg injection

ʻO Adipotide (aka FTPP a i ʻole proapototic peptide) e pepehi i nā momona momona, maʻalahi a maʻalahi hoʻi, ma ka huli ʻana i ke koko o kēlā mau cell.ʻO ka mea e mahalo ai, hiki i ka adipotide ke ʻike i nā kīʻaha koko i loko o nā momona momona mai nā kīʻaha koko ma ke koena o ke kino a no laila ke koho nui loa.Hōʻike ka noiʻi ʻana i nā monkey ʻaʻole ʻo adipotide wale nō ke kumu o ka pohō kaumaha, hoʻonui maoli ia i ka naʻau o ka insulin a hoʻopau i kekahi o nā hopena o ka maʻi diabetes type 2.

Hoʻohana Huahana: Ua manaʻo ʻia kēia huahana ma ke ʻano he noiʻi kemika WALE.ʻAe kēia inoa i ka hoʻohana ʻana i nā kemika noiʻi no ka hoʻāʻo in vitro a me ka hoʻokolohua hoʻokolohua wale nō.ʻO nā ʻike huahana āpau i loaʻa ma kēia pūnaewele no nā kumu hoʻonaʻauao wale nō.Ua kapu loa ia e ke kanawai ka hookomo kino ana i na kanaka a me na holoholona.Pono e mālama ʻia kēia huahana e nā poʻe loea i laikini ʻia.ʻAʻole kēia huahana he lāʻau lapaʻau, meaʻai, a mea hoʻomaʻemaʻe paha a ʻaʻole hiki ke kuhi hewa ʻia, hoʻohana hewa ʻia a kuhi hewa ʻia ma ke ʻano he lāʻau lapaʻau, meaʻai a mea hoʻonaninani paha.

Sequence: Cys-Lys-Gly-Gly-Arg-Ala-Lys-Asp-Cys—Gly-Gly–(Lys-Leu-Ala-Lys-Leu-Ala-Lys)2
Ke Kumu Molekala: C152H252N44O42
Kaumaha Molekala: 2611.41 g/mol

Ua hoʻomohala ʻia ʻo Adipotide a ua hoʻokomo ʻia i loko o nā hoʻokolohua lapaʻau o ka pae I i ka makahiki 2011 e noiʻi i kona hiki ke pepehi i nā mea momona.Ua hōʻike ʻia nā hoʻāʻo ʻana i nā monkey rhesus e kumu ka adipotide i ka apoptosis i manaʻo ʻia i loko o nā kīʻaha koko o ke kino adipose keʻokeʻo (momona).Me ka loaʻa ʻole o ke koko, make wale nā ​​mea momona.ʻO ka hopena ʻo ia ka hoʻoemi wikiwiki ʻana o ke kaumaha, ka emi wikiwiki ʻana o ka helu kino kino (BMI), a me ka hoʻomaikaʻi ʻana i nā ʻano kūʻē i ka insulin.ʻO ka mea e mahalo ai, ʻaʻole i hoʻomaikaʻi wale ka paona i ka mālama ʻana me ka adipotide a me ka lilo ʻana o ka momona, akā ua kōkua maoli i nā loli i ka ʻai ʻana.Ua hōʻike pū ʻia ka hoʻemi ʻana o ka ʻai ʻana o nā monkey me ka adipotide.1].

A. Paneka pākēneka o ka pohō kaumaha ma nā pū'ulu ho'omalu (uliuli) me ka po'e i mālama 'ia me adipotide ('elua mau kau'oko'a, hō'ike 'ia ma ka 'ula'ula)
B. Ka emi pākēneka o ka BMI (ka mālama ʻana me ka mālama ʻana)

A. Hōʻike i ka hoʻololi ʻana i nā koi o ka insulin (wahi ma lalo o ka pihi) no nā pūʻulu mālama ʻia (ʻulaʻula) a me ka (uliuli).Ua helu ʻia ka AUC mai kahi hōʻike IVGTT.
B. Hōʻike i ka insulinogenic index no ka mua a ma hope o ka mālama ʻana (ʻulaʻula) a me nā pūʻulu hoʻomalu (uliuli).Hōʻike nā hui i mālama ʻia i ka emi nui o ka huna ʻana o ka insulin.
C. Hoʻololi i ka ʻai ʻana i ka biscuit i nā hui mālama ʻia (ʻulaʻula) a me ka mana (uliuli).

Hiki ke hoʻopili ʻia ka hoʻopaʻa ʻana o adipotide i nā kīʻaha koko e lawelawe ana i nā sela momona e kahi mea hoʻokipa protein i kapa ʻia ʻo prohibitin.ʻO ka Prohibitin kahi protein membrane i loaʻa wale i loko o nā kīʻaha koko e lawelawe ana i ka momona keʻokeʻo a i loko o nā maʻi kanesa.Ua hōʻike ʻia e pili ana ka adipotide me kēia protein [2].Inā ʻike ʻia ka pāpā ʻana i loaʻa wale i loko o ka vasculature momona a me ka ʻiʻo maʻi maʻi, a laila ʻo ka hoʻāʻo adipotide ke kuleana no ka ʻike ʻana i kahi pahuhopu kikoʻī momona hiki ke hoʻohana ʻia ʻaʻole wale no nā kumu therapeutic, akā no nā kumu diagnostic pū kekahi.