Hāʻawi ʻo Kina i nā Sarms Raw Sr9009 Stenabolic API

ʻO REV-ERBα a me REV-ERBβ nā mea hoʻokipa nuklea he mau mea hoʻopiʻi transcriptional e hoʻonohonoho i ka circadian rhythm a me nā ala metabolic ma kahi ʻano heme.ʻO SR9009 kahi agonist REV-ERB e hoʻonui ana i ka repression constitutive o nā genes i hoʻoponopono ʻia e REV-ERBα a me REV-ERBβ me nā waiwai IC50 o 670 a me 800 nM.1Ma o ka ho'ā ʻana o REV-ERB, ua hōʻike ʻia ʻo SR9009 e hoʻemi i ka hana locomotor circadian i ka wā pōʻeleʻele a hoʻololi i ke ʻano o ka hōʻike ʻana o nā genes clock clock i ka hypothalami o nā ʻiole.1Ua hōʻike pū ʻia ke ʻano circadian o ka hōʻike ʻana o kahi ʻano o nā genes metabolic i loko o ke akepaʻa, ka ʻiʻo iwi a me ka ʻiʻo adipose i hoʻololi ʻia i nā ʻiole i hōʻike ʻia i ka SR9009, ka hopena o ka hoʻonui ʻana i ka ikehu. Ua hōʻike ʻia ʻo SR9009 (ip ʻelua manawa i ka lā no 30 mau lā) e hōʻike i ka emi ʻana o ka momona momona a me ka maikaʻi loa o ka dyslipidemia a me ka hyperglycemia.1

WARNING ʻAʻole kēia huahana no ke kanaka a i ʻole ka lāʻau holoholona.